Search results for "Functional importance"
showing 10 items of 10 documents
Differences in contractile behaviour between the soleus and medial gastrocnemius muscles during human walking
2012
The functional roles of individual lower limb muscles during human walking may differ depending on walking speed or duration. In this study, 11 volunteers walked on a treadmill for 60 min at speeds corresponding to both optimal and 20% above optimal energetic cost of transport whilst oxygen consumption and medial gastrocnemius (MG) and soleus fascicle lengths were measured. Although energetic cost of transport was ∼12% higher at the faster speed, it remained constant over 60 min at both speeds, suggesting that humans can walk for prolonged periods at a range of speeds without compromising energetic efficiency. The fascicles of both muscles exhibited rather ‘isometric’ behaviour during the e…
A Metalloligand Approach for the Self-Assembly of a Magnetic Two-Dimensional Grid-of-Grids
2019
The efficient organization of discrete functional molecules into extended frameworks, while retaining their physical properties, is a mandatory requisite to move toward applications. Here we descri...
The Vascularization of Experimental and Human Primary Tumors: Comparative Morphometric and Morphologic Studies
1998
The importance of the blood vessel system in solid tumors has given rise to an increasing interest in this system as a direct target for tumor therapy, i.e. vascular targeting (Denekamp, 1984). Furthermore, its importance as a route for delivery of anticancer drugs (chemo- and immunotherapies) or photosensitizers (photodynamic laser therapy), as well as its modulatory influences on radiotherapy and hyperthermia — the former greatly depending on the amount of oxygen available, the latter on heat transfer — are evident. Numerous studies on the energy metabolism of solid tumors (Vaupel et al., 1987, 1989) have pointed out the functional importance of the blood vessel system and stress the need…
Fine Structure of the Tunic ofCiona intestinalisL. II. Tunic morphology, cell distribution and their functional importance
1981
Ciona intestinalis L. tunic architecture and cell distribution were investigated with the electron microscope. The observations showed that the ascidian covering is formed by a thin outer cuticle, a subcuticle of variable width and a large single layer of ground substance. “Large granule”, morula, phagocyte and granulocyte are the cellular types encountered; they appear mainly in highly vacuolated states and are distributed throughout the whole tunic. The “large granule” cells, however, are mainly seen in the cuticle layer and the morula cells appear mostly in the outer zone of the ground substance. The role of these cells in tunic construction, repair and regeneration as well as their scav…
Single-Crystal-to-Single-Crystal Anion Exchange in a Gadolinium MOF: Incorporation of POMs and [AuCl4]−
2016
The encapsulation of functional molecules inside porous coordination polymers (also known as metal-organic frameworks, MOFs) has become of great interest in recent years at the field of multifunctional materials. In this article, we present a study of the effects of size and charge in the anion exchange process of a Gd based MOF, involving molecular species like polyoxometalates (POMs), and [AuCl4]−. This post-synthetic modification has been characterized by IR, EDAX, and single crystal diffraction, which have provided unequivocal evidence of the location of the anion molecules in the framework.
Response to Skeide and Friederici: The myth of the uniquely human “direct” dorsal pathway
2015
In their comment on our recent article [1], Skeide and Friederici [2] claim ‘that some important data not discussed by Bornkessel-Schlesewsky et al. strongly support the view that there are clear qualitative, and not merely quantitative, differences between [human and nonhuman primate] species with respect to both the intrinsic functional connectivity of frontal and temporal cortices, and their direct structural connection via a dorsal white matter fiber tract.’ This obviously refers to work by Friederici and colleagues [3] emphasizing the functional importance of a direct connection between the posterior superior temporal cortex (pSTC) and Brodmann area (BA) 44 in humans, and its absence i…
L’èxtasi poètic de Fontanella: metateatre i música a la Lloa per la Tragicomèdia pastoral d’amor, firmesa i porfia
2018
Resum: En absència d’estudis monogràfics sobre la Lloa de Fontanella, aquest article n’ analitza l’estructura dramàtica, començant amb una reflexió sobre llur classificació dintre del gènere i sobre l’espai de la Barcelona del segle XVII que podria haver-la escenificat. La importància funcional que el poeta barceloní atorga a la música i al metateatre condueixen a una interpretació de la Lloa des d’un punt de vista poeticomusical, la qual cosa permet una nova lectura de certs passatges i una valoració crítica que afecta, no només a la peça en qüestió sinó a tota la Tragicomèdia pastoral d’amor, firmesa i porfia i al caràcter d’avantguarda del teatre català de l’Edat Moderna
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The role of the thalamus in the human subcortical vestibular system1
2014
Most of our knowledge concerning central vestibular pathways is derived from animal studies while evidence of the functional importance and localization of these pathways in humans is less well defined. The termination of these pathways at the thalamic level in humans is even less known. In this review we summarize the findings concerning the central subcortical vestibular pathways in humans and the role of these structures in the central vestibular system with regard to anatomical localization and function. Also, we review the role of the thalamus in the pathogenesis of higher order sensory deficits such as spatial neglect, pusher syndrome or thalamic astasia and the correlation of these p…
Engineered Multifunctional Nanotools for Biological Applications
2011
Smart multifunctional magnetic nanoparticles are popular candidates for several biological applications owing to their intrinsic magnetic property and diverse applications that range from rare protein separation and biomedical utilization to cancer therapy and diagnostics. A universal protocol, for the development of such nanocarriers, is highly desirable for scientists with different backgrounds so that custom-made multifunctional nanoparticles can be developed to address their needs, among which are the superparamagnetic iron oxide and manganese oxide nanoparticles that are synthesized through high temperature decomposition reactions. However, an interface is needed to present these inorg…